According to an analysis by the federal Centers for Disease Control and Prevention published Tuesday (April 6) most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows. (NIAID-RML via AP, File)

According to an analysis by the federal Centers for Disease Control and Prevention published Tuesday (April 6) most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows. (NIAID-RML via AP, File)

Most kids with serious inflammatory illness had mild COVID-19

The post-infection condition tends to be milder in kids who were sicker with COVID-19, although more than half received intensive hospital care

Most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows.

The unusual post-infection condition tends to be milder in kids who were sicker with COVID-19, although more than half of affected youngsters received intensive hospital care, according to an analysis by the federal Centers for Disease Control and Prevention published Tuesday in JAMA Pediatrics.

The study represents the largest analysis to date on U.S. cases of multisystem inflammatory syndrome in children and bolsters evidence that it is a delayed immune response to COVID-19. The study included almost 1,800 cases reported to the CDC from March 2020 through mid-January. Most were in kids younger than 15 but the study included up to age 20.

Upticks in cases have occurred two to five weeks after COVID-19 peaks and have followed spread of initial infections from urban to rural areas, the researchers said. More recent CDC data indicate there’s another emerging peak in the pediatric condition consistent with that trend.

State-reported cases through March 29 totalled 3,185 and included 36 deaths, the CDC’s website shows. State reports aren’t always timely so it is uncertain how many U.S. children developed the illness since the study ended.

Most kids who had COVID-19 don’t develop post-infection illness. Almost 3.5 million U.S. children and teens have tested positive for COVID-19, according to data compiled by the American Academy of Pediatrics and the Children’s Hospital Association.

The condition was first reported in Europe in late winter and spring of last year. Some cases, especially those that follow silent, undiagnosed COVID-19 infections, may be mistaken for Kawasaki disease, a rare condition that can cause red skin, swelling and heart problems.

Dr. Sean O’Leary, vice chairman of the pediatrics academy’s infectious diseases committee, said the inflammatory condition typically causes children to become very sick very quickly, but that most ‘’respond very well to treatment and the vast majority get completely better.’’

Treatments may include steroids and other medicines that can reduce inflammation.

The best way to prevent it is to prevent COVID-19 infections, ‘’which vaccines are very good at doing,’’ he said. COVID-19 vaccine studies in children are underway.

In the CDC analysis, fever was among the most common symptoms. Abdominal pain, vomiting, diarrhea and red skin rash occurred in at least half of affected kids. Almost one-third had heart inflammation or other cardiac involvement. These symptoms were least common among children up to age 4, who were also less likely to require intensive care than older children.

CoronavirusHealth

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Kimberley case counts not at the point for 18 years and older community vaccination, says Interior Health. (File photo)
Many factors considered for smaller community-wide vaccination: Interior Health

East Kootenay resort town’s COVID-19 situation not at the point of community-wide vaccination, say officials

A woman wears a protective face covering to help prevent the spread of COVID-19 as she walks past the emergency entrance of Vancouver General Hospital in Vancouver, B.C., Friday, April 9, 2021. THE CANADIAN PRESS/Jonathan Hayward
54 more cases of COVID-19 in Interior Health

Thirty-two people in the region are in hospital with the virus, 11 of them in intensive care

While pharmacies across B.C. are using AstraZeneca for public immunizations for people 40 years of age and older, there is no availability currently in the Kootenays. (AP Photo/Frank Augstein)
No AstraZeneca vaccine availability in Kootenay pharmacies, says Interior Health

Vaccine has been opened up at pharmacies in other areas of the province to people 40 years of age and older

Michel-Natal-Sparwood Heritage Society runs a museum that was established to display the heritage of the "no-longer towns" of Michel and Natal, and the Elk Valley Area. Photo Submitted/Monica Beranek, Artifact Curator
Sparwood to support museum financially through to December 2022

The district will provide financial support for the museum to hire a full-time director

B.C. Finance Minister Selina Robinson outlines the province’s three-year budget in Victoria, April 20, 2021. (B.C. government video)
B.C. deficit to grow by $19 billion for COVID-19 recovery spending

Pandemic-year deficit $5 billion lower than forecast

Canadian Prime Minister Justin Trudeau and United States President Joe Biden smile as they say farewell following a virtual joint statement in Ottawa, Tuesday, February 23, 2021. THE CANADIAN PRESS/Adrian Wyld
Trudeau pledges to cut emissions by 40% to 45% by 2030, short of U.S. goal

Trudeau announced target during a virtual climate summit convened by U.S. President Joe Biden

MLA Shirley Bond, right, answers questions during a press conference at Legislature in Victoria, B.C., on February 19, 2019. THE CANADIAN PRESS/Chad Hipolito
Former B.C. gaming minister says she wasn’t told directly about dirty cash flowing to casinos

Shirley Bond said Thursday civil forfeiture, gang violence and gambling addiction were also major concerns in 2011

RCMP Constable Etsell speaks to tourists leaving the area at a police roadblock on Westside Road south of Fintry, B.C., Thursday, July 23, 2009. THE CANADIAN PRESS/ Yvonne Berg
B.C. police say they take ‘exception’ to conducting roadblocks limiting travel

Asking the police to enforce roadblocks exposes officers to further risk and possible COVID-19 infections, says federation president Brian Sauve

Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

As part of the province’s strategy to combat the opioid overdose crisis, take-home naloxone kits have been distributed throughout the province. (Courtesy of Gaëlle Nicolussi)
Vancouver Island could be at its worst point of overdose crises yet: medical health officer

Island Health issued overdose advisories for Victoria, various communities in the last two weeks

BC Hydro released a survey Thursday, April 22. It found that many British Columbians are unintentionally contributing to climate change with their yard maintenance choices. (Pixabay)
Spend a lot of time doing yard work? It might be contributing to climate change

Recent BC Hydro survey finds 60% of homeowners still use gas-powered lawnmowers and yard equipment

Journal de Montreal is seen in Montreal, on Thursday, April 22, 2021. The daily newspaper uses a file picture of Prime Minister Justin Trudeau dressed in traditional Indian clothing during his trip to India to illustrate a story on the Indian variant of the coronavirus. Paul Chiasson/The Canadian Press
Montreal newspaper blasted for front-page photo of Trudeau in India

Trudeau is wearing traditional Indian clothes and holding his hands together in prayer beside a caption that reads, ‘The Indian variant has arrived’

Nanaimo RCMP say a man was injured while pouring gunpowder on a backyard fire in Harewood on Wednesday, April 21. (File photo)
Nanaimo man hospitalized after pouring gunpowder onto backyard fire

RCMP investigating explosion in Harewood also came across a still for making alcohol on property

Most Read